(S)-2-AMINO-3-(CARBOXYFORMAMIDO)PROPANOIC ACID

Names

[ Name ]:
(S)-2-AMINO-3-(CARBOXYFORMAMIDO)PROPANOIC ACID

[Synonym ]:
ODAP
β-N-oxalyl-L-α,β-diaminopropionic acid
(2-Amino-2-carboxyethyl)-L-oxamic acid
L-Alanine, 3-[(carboxycarbonyl)amino]-
3-[(Carboxycarbonyl)amino]-alanine
BOAA
(2S)-2-Amino-3-[(carboxycarbonyl)amino]propanoic acid
Dencichine
β-ODAP
3-[(Carboxycarbonyl)amino]-L-alanine
β-N-Oxalylamino-L-alanine
(S)-2-Amino-3-(carboxyformamido)propanoic acid
Oxalyldiaminopropionic acid

Biological Activity

[Description]:

(Rac)-Dencichin (2-Amino-3-(carboxyformamido)propanoic acid) is the racemate of Dencichin. Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Eslavath RK, et al. β-N-oxalyl-L-α, β- diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions. Eur J Pharmacol. 2016 Nov 15;791:405-411.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₅H₈N₂O₅

[ Molecular Weight ]:
176.127

[ Exact Mass ]:
176.043320

[ PSA ]:
129.72000

[ LogP ]:
-1.51

[ Index of Refraction ]:
1.556

Safety Information

[ HS Code ]:
2924199090

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%