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Gomisin K1

Names

[ CAS No. ]:
75629-20-8

[ Name ]:
Gomisin K1

[Synonym ]:
D445L37O09
Gomisin K1
Gomisin K2
UNII:D445L37O09
111FHP5Z80
(6S,7R)-1,2,10,11,12-Pentamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-3-ol
Dibenzo[a,c]cycloocten-3-ol, 5,6,7,8-tetrahydro-1,2,10,11,12-pentamethoxy-6,7-dimethyl-, (6S,7R)-
UNII:111FHP5Z80

Biological Activity

[Description]:

Gomisin K1 ((-)-Gomisin K1) is a lignan that exhibits anti-cancer activity. Gomisin K1 inhibits HeLa cell growth, with an IC50 of 5.46 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Choi SK, et, al. Dibenzocyclooctadiene lignans from the fruits of Schisandra chinensis and their cytotoxicity on human cancer cell lines. Appl Biol Chem 63, 39 (2020).

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
563.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H30O6

[ Molecular Weight ]:
402.48

[ Flash Point ]:
294.8±30.1 °C

[ Exact Mass ]:
402.204254

[ LogP ]:
5.34

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.536

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds