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11-trans Leukotriene E4

Names

[ CAS No. ]:
75715-88-7

[ Name ]:
11-trans Leukotriene E4

[Synonym ]:
(5S,6R,7E,9E,11E,14Z)-6-{[(2R)-2-Amino-2-carboxyethyl]sulfanyl}-5-hydroxy-7,9,11,14-icosatetraenoic acid
7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11E,14Z)-

Biological Activity

[Description]:

11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. S Hammarström, et al. Metabolism of leukotrienes. Mol Cell Biochem. 1985 Nov;69(1):7-16.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
674.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H37NO5S

[ Molecular Weight ]:
439.609

[ Flash Point ]:
361.5±31.5 °C

[ Exact Mass ]:
439.239258

[ PSA ]:
146.15000

[ LogP ]:
5.65

[ Vapour Pressure ]:
0.0±4.7 mmHg at 25°C

[ Index of Refraction ]:
1.557

Related Compounds