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Phthalic Acid Anhydride-d4

Names

[ CAS No. ]:
75935-32-9

[ Name ]:
Phthalic Acid Anhydride-d4

[Synonym ]:
Tetradeuterio-phthalsaeureanhydrid
Phthalic anhydride-d4
d4-phthalic anhydride
phthalic acid anhydride-d4
MFCD00145119

Biological Activity

[Description]:

Phthalic Acid Anhydride-d4 is the deuterium labeled Phthalic Acid Anhydride-d4[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.483g/cm3

[ Boiling Point ]:
284ºC(lit.)

[ Melting Point ]:
131-134ºC(lit.)

[ Molecular Formula ]:
C8D4O3

[ Molecular Weight ]:
152.14000

[ Flash Point ]:
139.7ºC

[ Exact Mass ]:
152.04100

[ PSA ]:
43.37000

[ LogP ]:
0.99720

[ Index of Refraction ]:
1.612

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H317-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN 2214 8/PG 3

Synthetic Route

Precursor & DownStream


Related Compounds