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Clematichinenoside AR

Names

[ CAS No. ]:
761425-93-8

[ Name ]:
Clematichinenoside AR

Biological Activity

[Description]:

Clematichinenoside AR is a major active ingredient that could be extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects on various diseases, including atherosclerosis (AS)[1].

[Related Catalog]:

Signaling Pathways >> Autophagy >> Autophagy
Research Areas >> Inflammation/Immunology

[In Vitro]

Clematichinenoside AR alleviates foam cell formation and the inflammatory response in Ox-LDL-induced RAW264.7 cells by activating autophagy[1].

[In Vivo]

Clematichinenoside AR induces immunosuppression involving Treg cells in Peyer's patches of rats with adjuvant induced arthritis[2].

[References]

[1]. Yajing Diao, et al. Clematichinenoside AR Alleviates Foam Cell Formation and the Inflammatory Response in Ox-LDL-Induced RAW264.7 Cells by Activating Autophagy. Inflammation. 2021 Apr;44(2):758-768.

[2]. Ying Xiong, et al. Clematichinenoside AR induces immunosuppression involving Treg cells in Peyer׳s patches of rats with adjuvant induced arthritis. J Ethnopharmacol. 2014 Sep 11;155(2):1306-14.

Chemical & Physical Properties

[ Density]:
1.58±0.1 g/cm3

[ Molecular Formula ]:
C82H134O43

[ Molecular Weight ]:
1807.93

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds