Florfenicol amine

Names

[ Name ]:
Florfenicol amine

[Synonym ]:
Florfenicol amine

Biological Activity

[Description]:

Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, is used in aquaculture to control susceptible bacterial diseases[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. B-K Park, et al. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus). J Vet Pharmacol Ther. 2006 Feb;29(1):37-40.

Chemical & Physical Properties

[ Density]:
1.313±0.06 g/cm3

[ Boiling Point ]:
488.7±45.0 °C

[ Molecular Formula ]:
C₁₀H₁₄FNO₃S

[ Molecular Weight ]:
247.28600

[ Exact Mass ]:
247.06800

[ PSA ]:
88.77000

[ LogP ]:
2.20140

[ Appearance of Characters ]:
neat

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Development and validation of determinative and confirmatory LC-MS/MS methodologies for total florfenicol and tulathromycin residues in bovine, equine and porcine kidney, liver and muscle tissues.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 983-984 , 1-9, (2015)

Separate methods for the quantitation and confirmation of regulatory relevant residue concentrations of total florfenicol and tulathromycin residues in multiple tissue matrices were developed and vali...

Florfenicol Residues in Rainbow Trout after Oral Dosing in Recirculating and Flow-through Culture Systems.

J. Aquat. Anim. Health 26(4) , 243-50, (2014)

Abstract Aquaflor is a feed premix for fish containing the broad spectrum antibacterial agent florfenicol (FFC) incorporated at a ratio of 50% (w/w). To enhance the effectiveness of FFC for salmonids ...

Multiresidue method for the simultaneous determination of veterinary medicinal products, feed additives and illegal dyes in eggs using liquid chromatography-tandem mass spectrometry.

Food Chem. 197 , 571-80, (2015)

A multiclass method was developed for the simultaneous determination of 120 analytes in fresh eggs. The method covers the analytes from the groups of tetracyclines (6), fluoroquinolones (11), sulphona...