Fluorescein-5-thiosemicarbazide

Names

[ Name ]:
Fluorescein-5-thiosemicarbazide

[Synonym ]:
5-(aminocarbamothioylamino)-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid

Biological Activity

[Description]:

Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Zhang Y, et al. One-pot fluorescent labeling of saccharides with fluorescein-5-thiosemicarbazide for imaging polysaccharides transported in living cells. Carbohydr Res. 2011 Oct 18;346(14):2156-64.

[2]. Havé M, et al. Protein carbonylation during natural leaf senescence in winter wheat, as probed by fluorescein-5-thiosemicarbazide. Plant Biol (Stuttg). 2015 Sep;17(5):973-9.

Chemical & Physical Properties

[ Boiling Point ]:
742.2ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₅N₃O₆

[ Molecular Weight ]:
405.36000

[ Flash Point ]:
402.7ºC

[ Exact Mass ]:
405.09600

[ PSA ]:
143.14000

[ LogP ]:
3.82520

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Cardiovascular disease-related parameters and oxidative stress in SHROB rats, a model for metabolic syndrome.

PLoS ONE 9(8) , e104637, (2014)

SHROB rats have been suggested as a model for metabolic syndrome (MetS) as a situation prior to the onset of CVD or type-2 diabetes, but information on descriptive biochemical parameters for this mode...

Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions.

PLoS Genet. 10(1) , e1004090, (2014)

The four-subunit Negative Elongation Factor (NELF) is a major regulator of RNA Polymerase II (Pol II) pausing. The subunit NELF-E contains a conserved RNA Recognition Motif (RRM) and is proposed to fa...

Deoxygenation affects fluorescence photobleaching recovery measurements of red cell membrane protein lateral mobility.

Biophys. J. 66 , 25, (1994)

We have used the fluorescence photobleaching recovery technique to study the dependence on oxygen tension of the lateral mobility of fluorescently labeled band 3, the phospholipid analogue fluorescein...