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Dehydropachymic acid

Names

[ CAS No. ]:
77012-31-8

[ Name ]:
Dehydropachymic acid

[Synonym ]:
Lanosta-7,9(11)-dien-21-oic acid, 3-(acetyloxy)-16-hydroxy-24-methylene-, (3β,16α)-
(3β,16α)-3-Acetoxy-16-hydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid
9-Dehydropachymic acid

Biological Activity

[Description]:

Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells[1].

[Related Catalog]:

Signaling Pathways >> Autophagy >> Autophagy
Research Areas >> Neurological Disease

[References]

[1]. Yu M, et al. Dehydropachymic acid decreases bafilomycin A1 induced β-Amyloid accumulation in PC12 cells. J Ethnopharmacol. 2017 Feb 23;198:167-173.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
629.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C33H50O5

[ Molecular Weight ]:
526.747

[ Flash Point ]:
192.1±25.0 °C

[ Exact Mass ]:
526.365845

[ LogP ]:
8.16

[ Vapour Pressure ]:
0.0±4.2 mmHg at 25°C

[ Index of Refraction ]:
1.549

[ Storage condition ]:
2-8℃

Related Compounds