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Glycolic acid oxidase inhibitor 1

Names

[ CAS No. ]:
77529-42-1

[ Name ]:
Glycolic acid oxidase inhibitor 1

[Synonym ]:
Glycolic acid oxidase inhibitor 1

Biological Activity

[Description]:

Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

Glycolate oxidase[1]


[In Vivo]

Glycolic acid oxidase inhibitor 1 inhibits oxalate biosynthesis in isolated perfused rat liver. Glycolate oxidase inhibitors provide a specific approach to the prevention and treatment of calcium oxalate renal lithiasis[1].

[References]

[1]. Cragoe Jr., Edward J, et al. 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same.EP0021228A1.


[Related Small Molecules]

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Chemical & Physical Properties

[ Density]:
1.641g/cm3

[ Boiling Point ]:
528.9ºC at 760 mmHg

[ Molecular Formula ]:
C16H10BrNO3

[ Molecular Weight ]:
344.16000

[ Flash Point ]:
273.7ºC

[ Exact Mass ]:
342.98400

[ PSA ]:
69.89000

[ LogP ]:
3.31750

[ Index of Refraction ]:
1.688

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds