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BAM-3200

Names

[ CAS No. ]:
78355-50-7

[ Name ]:
BAM-3200

[Synonym ]:
chembl506884
Peptide E proenkephalin
Peptide E (ox adrenal medulla)
Peptide E
Proenkephalin peptide E
Opioid peptide E
Peptide E (adrenal medulla)
YGGFMRRVGRPEWWMDYQKRYGGFL

Biological Activity

[Description]:

Peptide E is a potent kappa opiate receptor agonist. Peptide E has opiate receptor binding activity with IC50 value of 0.39 μM. Peptide E can be used for the research of central nervous system[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor
Signaling Pathways >> Neuronal Signaling >> Opioid Receptor
Research Areas >> Neurological Disease

[In Vitro]

Peptide E 具有阿片受体结合活性，IC50 值为 0.39 μM[1]。

[References]

[1]. E P Heimer, et al. Synthesis of adrenal peptide E and some of its biological activities. Arch Biochem Biophys. 1983 Sep;225(2):518-24.  

[2]. R Quirion, et al. Peptide E and other proenkephalin-derived peptides are potent kappa opiate receptor agonists. Peptides. 1983 Jul-Aug;4(4):445-9.  

Chemical & Physical Properties

[ Molecular Formula ]:
C147H207N41O34S2

[ Molecular Weight ]:
3156.60000

[ Exact Mass ]:
3154.52000

[ PSA ]:
1287.11000

[ LogP ]:
9.26360

Related Compounds