Demethylasterriquinone B1

Names

[ Name ]:
Demethylasterriquinone B1

[Synonym ]:
Demethylasterriquinone B1

Biological Activity

[Description]:

Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> PI3K/Akt/mTOR >> Akt

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor

[References]

[1]. Li M, et al. Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells. Diabetes. 2001;50(10):2323-2328.

Chemical & Physical Properties

[ Density]:
1.335g/cm3

[ Boiling Point ]:
780.2ºC at 760 mmHg

[ Molecular Formula ]:
C₃₂H₃₀N₂O₄

[ Molecular Weight ]:
506.59200

[ Flash Point ]:
425.6ºC

[ Exact Mass ]:
506.22100

[ PSA ]:
106.18000

[ LogP ]:
7.01170

[ Index of Refraction ]:
1.72

Demethylasterriquinone B1

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds