N-Bromoacetamide

Names

[ CAS No. ]:
79-15-2

[ Name ]:
N-Bromoacetamide

[Synonym ]:
N-BROMOACETAMIDE
N-bromo-acetamide
MFCD00037097
EINECS 201-181-0
sJYHIabIKTp@
Acetamide,N-bromo
Lopac-B-2377

Biological Activity

[Description]:

N-Bromoacetamide can irreversibly remove sodium channel inactivation in the cytoplasmic face of the membrane, also decreasing K current rapid inactivation[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Others

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[Target]

Sodium channel, Potassium channel[1][2]

[References]

[1]. Matteson DR, et al. Modification of K channel inactivation by papain and N-bromoacetamide. Biophys J. 1988;53(4):641-645.

[2]. Patlak J, et al. Effect of N-bromoacetamide on single sodium channel currents in excised membrane patches. J Gen Physiol. 1982;79(3):333-351.

Chemical & Physical Properties

[ Density]:
1.71 g/cm3

[ Melting Point ]:
102-105°C

[ Molecular Formula ]:
C₂H₄BrNO

[ Molecular Weight ]:
137.96

[ Exact Mass ]:
136.94800

[ PSA ]:
29.10000

[ LogP ]:
0.82330

[ Index of Refraction ]:
1.474

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
3261

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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