NLRP3/AIM2-IN-2

Names

[ Name ]:
NLRP3/AIM2-IN-2

Biological Activity

[Description]:

NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and aim2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 ± 0.0233 μ M。

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

NLRP3 and AIM2:0.2392±0.0 μM (IC50)

[References]

[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₅NO₃

[ Molecular Weight ]:
257.28

[ Storage condition ]:
-20°C

NLRP3/AIM2-IN-2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds