Sulfachloropyridazine

Names

[ CAS No. ]:
80-32-0

[ Name ]:
Sulfachloropyridazine

[Synonym ]:
SULFACHLOROPYRIDAZINE
EINECS 201-269-9
4-Amino-N-(6-chloropyridazin-3-yl)-benzenesulfonamide
MFCD00057371

Biological Activity

[Description]:

Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Infection

[References]

[1]. Dirany A, et al. Electrochemical treatment of the antibiotic sulfachloropyridazine: kinetics, reaction pathways, and toxicity evolution. Environ Sci Technol. 2012 Apr 3;46(7):4074-82.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.588 g/cm3

[ Boiling Point ]:
559.7ºC at 760 mmHg

[ Melting Point ]:
186-187ºC

[ Molecular Formula ]:
C₁₀H₉ClN₄O₂S

[ Molecular Weight ]:
284.72200

[ Flash Point ]:
292.3ºC

[ Exact Mass ]:
284.01300

[ PSA ]:
106.35000

[ LogP ]:
3.24800

[ Index of Refraction ]:
1.6300 (estimate)

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
0.5 M NaOH: soluble50mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R43

[ Safety Phrases ]:
S36/S37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Supported liquid membrane-protected molecularly imprinted beads for micro-solid phase extraction of sulfonamides in environmental waters.

J. Chromatogr. A. 1357 , 158-64, (2014)

In this work, molecularly imprinted polymer (MIP) beads have been prepared and evaluated for the development of a supported liquid membrane-protected micro-solid phase extraction method for the analys...

Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.

Food Chem. 181 , 119-26, (2015)

A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UP...

The development and validation of a rapid method for the determination of antimicrobial agent residues in milk and meat using ultra performance liquid chromatography coupled to quadrupole--Orbitrap mass spectrometry.

J. Pharm. Biomed. Anal. 102 , 184-92, (2014)

A new multi-class method has been developed for the identification and quantification of the residues of 26 antibiotics from different classes (sulfonamides, macrolides, tetracyclines, penicillins, an...