Helicid

Names

[ Name ]:
Helicid

[Synonym ]:
2-formylphenyl beta-L-glucopyranoside
MFCD00210992
HILICIDUM
HEARTLEAFHOUTTUYNIAP.E.
Benzaldehyde, 4-(β-D-glucopyranosyloxy)-
Gynostemma
4-Formylphenyl β-D-glucopyranoside
Hiliedum
HELICIDUM
HELICIDE
Benzaldehyde, 4-(β-D-allopyranosyloxy)-
Helicid
4-Formylphenyl β-D-allopyranoside
4-Formylphenylb-D-allopyranoside

Biological Activity

[Description]:

Helicid (Helicide, Helicidum, 4-Formylphenyl-β-D-allopyranoside) is a major constituent of Helicia nilgirica Bedd. Helicid has been used to treat psychoneurosis for its sedative-hypnotic and analgesic properties[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vivo]

Helicid (8-32 mg/kg; given i.g.; once daily for 6 weeks) significantly reverses chronic unpredictable mild stress (CUMS)-induced depression-like behaviors in rats[1]. Animal Model: CUMS-induced depression rat model[1] Dosage: 8 mg/kg, 16 mg/kg, 32 mg/kg Administration: Given i.g.; once daily for 6 weeks Result: Improved CUMS-induced depression-like behavior in rats.

[References]

[1]. Tong J, et al. Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. Int Immunopharmacol. 2019 Feb;67:13-21.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
559.9±50.0 °C at 760 mmHg

[ Melting Point ]:
199-200°C

[ Molecular Formula ]:
C₁₃H₁₆O₇

[ Molecular Weight ]:
284.26

[ Flash Point ]:
215.8±23.6 °C

[ Exact Mass ]:
284.089600

[ PSA ]:
116.45000

[ LogP ]:
-1.04

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.651

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S26-S36/37/39-S45-S27

[ RIDADR ]:
3265

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2932999099

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%