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Pyracrenic acid

Names

[ CAS No. ]:
80832-44-6

[ Name ]:
Pyracrenic acid

[Synonym ]:
Pyracrenic acid
Betulinic Acid 3Beta-Caffeate
betulinic acid 3beta-transcaffeate

Biological Activity

[Description]:

Pyracrenic acid is an elastase inhibitor (IC50 = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity[1][2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Elastase
Research Areas >> Inflammation/Immunology

[In Vitro]

Pyracrenic acid 具有非常强的弹性蛋白酶抑制活性,IC50 值为 1.5 µg/mL (2.42 µM)[2]。

[References]

[1]. Otsuka H, et al. Studies on anti-inflammatory agents. V. A new anti-inflammatory constituent of Pyracantha crenulata roem. Chem Pharm Bull (Tokyo). 1981 Nov;29(11):3099-104.  

[2]. Kim J H, et al. Compounds with elastase inhibition and free radical scavenging activities from Callistemon lanceolatus. J Med Plants Res. 2009, 3(11): 914-920.

Chemical & Physical Properties

[ Molecular Formula ]:
C39H54O6

[ Molecular Weight ]:
618.84

[ Exact Mass ]:
618.39200

[ PSA ]:
104.06000

[ LogP ]:
8.76500

Precursor & DownStream

Precursor

DownStream


Related Compounds