(Trifluoromethyl)trimethylsilane

Names

[ Name ]:
(Trifluoromethyl)trimethylsilane

[Synonym ]:
Silane, trimethyl(trifluoromethyl)-
(trifluoromethyl)-trimethylsilane
Trifluoromethyl(trimethyl)silane
Trimethyl(trifluoromethyl)silane
(Trifluoromethyl)trimethylsilane
MFCD00145454

Biological Activity

[Description]:

Trimethylsilyl(trifluoromethyl)silane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

(Trifluoromethyl)trimethylsilane 被用作亲电底物三氟甲基化的有价值试剂。它还用于三氟甲基对醛和酮的亲核加成。它与催化量的 F-（TBAF 或 CsF）生成三氟甲基，并与羰基化合物反应生成三氟甲基化醇。

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
49.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₉F₃Si

[ Molecular Weight ]:
142.19

[ Flash Point ]:
-16.4±27.3 °C

[ Exact Mass ]:
142.042557

[ LogP ]:
1.85

[ Vapour Pressure ]:
313.6±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.328

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Supplemental HS ]:
May form explosive peroxides.

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F:Flammable;Xi:Irritant;

[ Risk Phrases ]:
R11;R19;R36/37

[ Safety Phrases ]:
S16-S33-S39-S26-S36-S29

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF.

J. Org. Chem. 71 , 6806, (2006)

Organofluorine compounds are becoming increasingly important in different fields, such as material science, agro chemistry, and the pharmaceutical industry. Nucleophilic trifluoromethylation is one of...