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m-PEG8-Tos

Names

[ CAS No. ]:
82217-01-4

[ Name ]:
m-PEG8-Tos

Biological Activity

[Description]:

Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H42O11S

[ Molecular Weight ]:
538.65

[ Storage condition ]:
2-8°C

Related Compounds