11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

Names

[ Name ]:
11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

[Synonym ]:
MFCD00731281

Biological Activity

[Description]:

Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Bhagat K, et al. Microwave-assisted synthesis of 11-substituted-3,3-dimethyl-2,3,4,5,10,11-hexahydrodibenzo[b,e][1,4]diazepin-1-one derivatives catalysed by silica supported fluoroboric acid as potent antioxidant and anxiolytic agents. Med Chem Res 28, 2200–2217 (2019).

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
565.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₁N₃O₃

[ Molecular Weight ]:
363.41000

[ Flash Point ]:
295.8ºC

[ Exact Mass ]:
363.15800

[ PSA ]:
86.95000

[ LogP ]:
5.61590

[ Index of Refraction ]:
1.658

[ Storage condition ]:
-20°C

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream