Aztreonam (lysine)

Names

[ CAS No. ]:
827611-49-4

[ Name ]:
Aztreonam (lysine)

[Synonym ]:
aztreonam L-lysine salt

Biological Activity

[Description]:

Aztreonam (lysine) is a monocyclic beta-lactam antibiotic, and has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam (lysine) is active against Gram-negative aerobic bacteria[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4(5):516-26.  

[2]. Brogden RN, et al. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1986 Feb;31(2):96-130.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H31N7O10S2

[ Molecular Weight ]:
581.62000

[ Exact Mass ]:
581.15700

[ PSA ]:
327.54000

[ LogP ]:
1.74620

Related Compounds