Pyridoxine-d5 hydrochloride

Names

[ CAS No. ]:
82896-38-6

[ Name ]:
Pyridoxine-d5 hydrochloride

[Synonym ]:
Pyridoxine Hydrochloride D5

Biological Activity

[Description]:

Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):119-124.  

Chemical & Physical Properties

[ Molecular Formula ]:
C8H12ClNO3

[ Molecular Weight ]:
205.63900

[ Exact Mass ]:
205.05100

[ PSA ]:
73.58000

[ LogP ]:
0.88220

Related Compounds