D-Ala-Gly-Phe-Met-NH2

D-Ala-Gly-Phe-Met-NH2, an opioid peptide, is a potent opiate δ-receptor agonist[1].

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Research Areas >> Others

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

D-Ala-Gly-Phe-Met-NH2 (7.1 nM and 14.2 nM (0.5 μL); microinjection; male Sprague-Dawley rats) increases ethanol intake in preference to food in the nucleus accumbens (NAc)[1]. Animal Model: Male Sprague-Dawley rats (200-250 g)[1] Dosage: 7.1 nM and 14.2 nM (0.5 μL) Administration: Microinjection in the nucleus accumbens (NAc) Result: Increased ethanol intake in the nucleus accumbens (NAc).