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Platelet Factor 4 (58-70) (human)

Names

[ CAS No. ]:
82989-21-7

[ Name ]:
Platelet Factor 4 (58-70) (human)

[Synonym ]:
PRO-LEU-TYR-LYS-LYS-ILE-ILE-LYS-LYS-LEU-LEU-GLU-SER
H-PRO-LEU-TYR-LYS-LYS-ILE-ILE-LYS-LYS-LEU-LEU-GLU-SER-OH
platelet factor 4 fragment 58-70 human
L-Prolyl-L-leucyl-L-tyrosyl-L-lysyl-L-lysyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-lysyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-serine

Biological Activity

[Description]:

Platelet Factor 4 (58-70), human, a peptide based on the amino acid sequence corresponding to residues 58-70 of platelet factor-4 (PF-4), contains the major heparin-binding domain, which is not sufficient for full antiangiogenic activity[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Jouan V, et al. Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of action. Blood. 1999 Aug 1;94(3):984-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C76H133N17O18

[ Molecular Weight ]:
1572.97

[ Exact Mass ]:
1572.00000

[ PSA ]:
580.37000

[ LogP ]:
7.01330

[ Storage condition ]:
−20°C

[ Water Solubility ]:
Very soluble (1000 g/L) (25 ºC)

Safety Information

[ WGK Germany ]:
3

Related Compounds