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Diacetazotol

Names

[ CAS No. ]:
83-63-6

[ Name ]:
Diacetazotol

[Synonym ]:
Dimazon
Pellidole
Diacetotoluide
4'-Diacetylamino-2.3'-dimethyl-azobenzol
Pellidol
Diacetylaminoazotoluen
Dermagen
5-o-Toluolazo-2-diacetylamino-toluol
Diacetazotol
Dermagan
N-(2-methyl-4-o-tolylazo-phenyl)-diacetamide
4'-Diacetamino-2.3'-dimethyl-azobenzol
Epidermol
Diamazo
Periphermin
N-(2-Methyl-4-o-tolylazo-phenyl)-diacetamid
EINECS 201-490-0

Biological Activity

[Description]:

Diacetazotol inhibits dioxin-induced ethoxyresorufin-O-deethylase (EROD) activity with IC50 of 75±4 nM. Diacetazotol extracts from patent US20070032458, compound 3.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Infection

[Target]

IC50: 75±4 nM (Dioxin-induced EROD activity)[1]


[In Vitro]

Diacetazotol has activity for inhibiting dioxin toxicity[1].

[References]

[1]. Pann Suh, et al. Compound having activity for inhibiting dioxin toxicity, pharmaceutical composition comprising the compound and method for treating disease resulting from dioxin toxicity using the compound .US 20070032458 A1.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.11g/cm3

[ Boiling Point ]:
547.7ºC at 760 mmHg

[ Melting Point ]:
76ºC

[ Molecular Formula ]:
C18H19N3O2

[ Molecular Weight ]:
309.36200

[ Flash Point ]:
285.1ºC

[ Exact Mass ]:
309.14800

[ PSA ]:
62.10000

[ LogP ]:
4.61820

[ Index of Refraction ]:
1.575

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB4230000
CHEMICAL NAME :
Acetamide, N-acetyl-N-(2-methyl-4-((2-methylphenyl)azo)phenyl)-
CAS REGISTRY NUMBER :
83-63-6
BEILSTEIN REFERENCE NO. :
0686326
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H19-N3-O2
MOLECULAR WEIGHT :
309.40
WISWESSER LINE NOTATION :
1VNV1&R B DNUNR B

Safety Information

[ Risk Phrases ]:
45

[ Safety Phrases ]:
S53

[ HS Code ]:
2927000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds