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Raloxifene Bismethyl Ether

Names

[ CAS No. ]:
84541-38-8

[ Name ]:
Raloxifene Bismethyl Ether

[Synonym ]:
6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-piperidinylethoxy)benzoyl]benzo[b]thiophene
1-(2-{4-[6-methoxy-2-(4-methoxyphenyl)-benzo[b]thiophene-3-carbonyl]-phenoxy}-ethyl)-piperidine
Raloxifene Bismethyl Ether
(4-(2-(piperidin-1-yl)ethoxy)phenyl)(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)methanone
1-(2-{4-[6-Methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenoxy}-ethyl)-piperidin
[6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene][4-(2-(piperidin-1-yl)ethoxy)phenyl]methanone
6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene
[6-Methoxy-2-(4-methoxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone

Biological Activity

[Description]:

Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Raloxifene Bismethyl Ether has no effect on tissue toughness in the ex vivo beam model[1].

[References]

[1]. Gallant MA, et al. Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties. Bone. 2014 Apr;61:191-200.

Chemical & Physical Properties

[ Melting Point ]:
75-85ºC

[ Molecular Formula ]:
C30H31NO4S

[ Molecular Weight ]:
501.63600

[ Exact Mass ]:
501.19700

[ PSA ]:
76.24000

[ LogP ]:
6.61910

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds