Sudan III

Names

[ CAS No. ]:
85-86-9

[ Name ]:
Sudan III

[Synonym ]:
2-Naphthalenol, 1-[(E)-2-[4-[(Z)-2-phenyldiazenyl]phenyl]diazenyl]-
fatredr
MFCD00003905
D & C Red No. 17
EINECS 201-638-4
redzh
Oil Red (VAN)
1-[(E)-{4-[(Z)-Phenyldiazenyl]phenyl}diazenyl]-2-naphthol
Tony Red
AKA225
Tetrazobenzene-b-naphthol
OIL RED
Tetrazobenzene-β-naphthol
Sudan Red III
Oil Scarlet (VAN)
1-[(E)-{4-[(Z)-phenyldiazenyl]phenyl}diazenyl]naphthalen-2-ol
C.I. Solvent Red 23
SUDAN 3
RED 17
C.I. Solvent Red 23 (8CI)
Oil Scarlet
Sudan III
SUDAN
SUDAN G
c.i.23

Biological Activity

[Description]:

Sudan III is a lysochrome (fat-soluble dye) diazo dye.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
584.6±35.0 °C at 760 mmHg

[ Melting Point ]:
199 °C (dec.)(lit.)

[ Molecular Formula ]:
C₂₂H₁₆N₄O

[ Molecular Weight ]:
352.389

[ Flash Point ]:
398.1±15.2 °C

[ Exact Mass ]:
352.132416

[ PSA ]:
69.67000

[ LogP ]:
5.74

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.662

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QK4250000

CHEMICAL NAME :: 2-Naphthalenol, 1-((4-(phenylazo)phenyl)azo)-

CAS REGISTRY NUMBER :: 85-86-9

BEILSTEIN REFERENCE NO. :: 0931185

LAST UPDATED :: 199701

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C22-H16-N4-O

MOLECULAR WEIGHT :: 352.42

WISWESSER LINE NOTATION :: L66J BNUNR DNUNR&& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intrapleural

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 20 umol/L/5H (Continuous)

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,241,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,241,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81045 No. of Facilities: 650 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 5334 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81045 No. of Facilities: 437 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 7807 (estimated) No. of Female Employees: 5186 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R10;R20;R36/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QK4250000

[ HS Code ]:
2927000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

J. Chromatogr. Sci. 48(1) , 63-7, (2010)

A simple and sensitive high-performance liquid chromatography (HPLC) analytical method for the simultaneous determination of six Sudan dyes (Sudan Red G, Sudan I, Sudan II, Sudan III, Sudan Red 7B, Su...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

Determining the adulteration of spices with Sudan I-II-II-IV dyes by UV-visible spectroscopy and multivariate classification techniques.

Talanta 79(3) , 887-92, (2009)

We propose a very simple and fast method for detecting Sudan dyes (I, II, III and IV) in commercial spices, based on characterizing samples through their UV-visible spectra and using multivariate clas...