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H-Pro-Pro-Asp-NH2 trifluoroacetate salt

Names

[ CAS No. ]:
850440-85-6

[ Name ]:
H-Pro-Pro-Asp-NH2 trifluoroacetate salt

[Synonym ]:
L-Prolyl-L-prolyl-L-α-asparagine
L-α-Asparagine, L-prolyl-L-prolyl-

Biological Activity

[Description]:

H-Pro-Pro-Asp-NH2 is a potent and selective catalyst for asymmetric aldol reactions. H-Pro-Pro-Asp-NH2 catalyzes aldol reactions between acetone and several aldehydes[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Revell JD, et al. Solid-supported and pegylated H-Pro-Pro-Asp-NHR as catalysts for asymmetric aldol reactions. Biopolymers. 2006;84(1):105-13.  

[2]. Jefferson D. Revell, et al. Investigating Sequence Space: How Important is the Spatial Arrangement of Functional Groups in the Asymmetric Aldol Reaction Catalyst H-Pro-Pro-Asp-NH2? Advanced Synthesis & Catalysis, 2008, 1046-1052.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
733.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H22N4O5

[ Molecular Weight ]:
326.348

[ Flash Point ]:
397.3±32.9 °C

[ Exact Mass ]:
326.159027

[ LogP ]:
-1.46

[ Vapour Pressure ]:
0.0±5.2 mmHg at 25°C

[ Index of Refraction ]:
1.573

Related Compounds