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BML 284

Names

[ CAS No. ]:
853220-52-7

[ Name ]:
BML 284

[Synonym ]:
N-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine
MFCD09908087
2,4-Pyrimidinediamine, N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-
BML-284
Wnt agonist 1
CID 11210285 hydrochloride

Biological Activity

[Description]:

BML-284 is selective and cell-permeable Wnt signaling activator.

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> Wnt
Research Areas >> Cancer

[References]

[1]. Liu J, et al. A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl. 2005 Mar 18;44(13):1987-90.

[2]. Wang H, et al. 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine is an anti-inflammatory TLR-2, -4 and -5 response mediator in human monocytes. Inflamm Res. 2016 Jan;65(1):61-9.


[Related Small Molecules]

ICG-001 | Salinomycin | IWR-1 | Wnt-C59 | Berberine chloride hydrate | Pyrvinium pamoate | ETC-159 | IWP-2 | Heparan Sulfate | KYA 1797K | FH535 | SKL2001 | CCT251545 | iCRT-14 | NCB-0846

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
623.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H18N4O3

[ Molecular Weight ]:
350.371

[ Flash Point ]:
330.8±34.3 °C

[ Exact Mass ]:
350.137878

[ LogP ]:
3.72

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.684

[ Storage condition ]:
-20℃

Related Compounds