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(-)-Haplomyrfolin

Names

[ CAS No. ]:
85404-48-4

[ Name ]:
(-)-Haplomyrfolin

[Synonym ]:
(3S,4S)-3-Benzo[1,3]dioxol-5-ylmethyl-4-(4-hydroxy-3-methoxy-benzyl)-dihydro-furan-2-one
(+/-)-haplomyrfolin

Biological Activity

[Description]:

(-)-Haplomyrfolin is a natural lignan with anticancer effects[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

(-)-Haplomyrfolin (compound 8) 对人肺腺癌细胞(A549 细胞)显示出显着的细胞毒性,IC50 值为 0.273 μM[1]。

[References]

[1]. Li-Ping Liu, et al. Topoisomerase II inhibitors from the roots of Stellera chamaejasme L. Bioorg Med Chem. 2014 Aug 1;22(15):4198-203.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H20O6

[ Molecular Weight ]:
356.36900

[ Exact Mass ]:
356.12600

[ PSA ]:
74.22000

[ LogP ]:
2.70390


Related Compounds