(-)-Quinpirole hydrochloride
Names
[ CAS No. ]:
85798-08-9
[ Name ]:
(-)-Quinpirole hydrochloride
[Synonym ]:
Anandamide-d4
Quinpirole hydrochloride (USAN)
QUINPIROLE HYDROCHLORIDE
Quinpirole HCl
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Dopamine D2/D3 receptor[1].
[In Vivo]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.07g/cm3
[ Boiling Point ]:
383.9ºC at 760 mmHg
[ Molecular Formula ]:
C13H22ClN3
[ Molecular Weight ]:
255.78700
[ Flash Point ]:
186ºC
[ Exact Mass ]:
255.15000
[ PSA ]:
31.92000
[ LogP ]:
2.73880
[ Index of Refraction ]:
1.546
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR0809270
- CHEMICAL NAME :
- 1H-Pyrazolo(3,4-g)quinolone, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, monohydrochloride, (4aR-trans)-
- CAS REGISTRY NUMBER :
- 85798-08-9
- LAST UPDATED :
- 199403
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C13-H21-N3.Cl-H
- MOLECULAR WEIGHT :
- 255.83
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 600 ug/kg
- SEX/DURATION :
- female 10-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- PBBHAU Pharmacology, Biochemistry and Behavior. (ANKHO International Inc., P.O. Box 426, Fayetteville, NY 13066) V.1- 1973- Volume(issue)/page/year: 44,487,1993
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
UR0809270
Articles
Nat. Chem. Biol. 3(5) , 268-273, (2007)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...
Regulation of synaptic MAPK/ERK phosphorylation in the rat striatum and medial prefrontal cortex by dopamine and muscarinic acetylcholine receptors.J. Neurosci. Res. 93 , 1592-9, (2015)
Dopamine and acetylcholine are two principal transmitters in the striatum and are usually balanced to modulate local neural activity and to maintain striatal homeostasis. This study investigates the r...
Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues.Neuropsychopharmacology 40(6) , 1495-509, (2015)
A prominent aspect of drug addiction is the ability of drug-associated cues to elicit craving and facilitate relapse. Understanding the factors that regulate cue reactivity will be vital for improving...