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Latanoprostene bunod

Names

[ CAS No. ]:
860005-21-6

[ Name ]:
Latanoprostene bunod

[Synonym ]:
NCX-116
UNII-I6393O0922
Latanoprostene BUNOD

Biological Activity

[Description]:

Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Cavet ME, et al. The Role of Nitric Oxide in the Intraocular Pressure Lowering Efficacy of Latanoprostene Bunod: Review of Nonclinical Studies. J Ocul Pharmacol Ther. 2018 Jan/Feb;34(1-2):52-60.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H41NO8

[ Molecular Weight ]:
507.62

[ Exact Mass ]:
507.28300

[ PSA ]:
142.04000

[ LogP ]:
4.28970

Related Compounds