ARL 17477 dihydrochloride

Names

[ Name ]:
ARL 17477 dihydrochloride

Biological Activity

[Description]:

ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

[References]

[1]. Teiko Komori Nomura, et al. ARL-17477 is a dual inhibitor of NOS1 and the autophagic-lysosomal system that prevents tumor growth in vitro and in vivo. Sci Rep. 2023 Jul 4;13(1):10757.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₂Cl₃N₃S

[ Molecular Weight ]:
442.83

[ Exact Mass ]:
441.06000

[ PSA ]:
78.65000

[ LogP ]:
7.46600

ARL 17477 dihydrochloride

Names

Biological Activity

Chemical & Physical Properties

MSDS

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Related Compounds