Anti-inflammatory agent 34

Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

Anti-inflammatory agent 34 (Compound IVf) (200mg/kg; p.o.; single dose) 对角叉菜胶诱导的大鼠足水肿有抑制作用，对小鼠有缓解疼痛作用[1]。 Animal Model: Male albino rats, carrageenan-induced rat paw edema assay model[1] Dosage: 200 mg/kg Administration: Oral, single dose Result: Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h. Animal Model: Albino mice, acetic acid induced writhing method[1] Dosage: 200 mg/kg Administration: Oral, single dose Result: Showed 48.1% analgesic activity.

[1]. Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6.