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Benzyl-PEG4-Azido

Names

[ CAS No. ]:
86770-71-0

[ Name ]:
Benzyl-PEG4-Azido

[Synonym ]:
2,5,8,11-Tetraoxatridecane,13-azido-1-phenyl

Biological Activity

[Description]:

Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H23N3O4

[ Molecular Weight ]:
309.36100

[ Exact Mass ]:
309.16900

[ PSA ]:
86.67000

[ LogP ]:
2.01606

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Precursor & DownStream


Related Compounds