Benzyl-PEG6-azide

Names

[ CAS No. ]:
86770-73-2

[ Name ]:
Benzyl-PEG6-azide

[Synonym ]:
Benzyl-PEG6-azide

Biological Activity

[Description]:

Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₃₁N₃O₆

[ Molecular Weight ]:
397.46600

[ Exact Mass ]:
397.22100

[ PSA ]:
105.13000

[ LogP ]:
2.04926

Benzyl-PEG6-azide

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds