SID 7969543
Names
Biological Activity
[Description]:
SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily[1][2].
[Related Catalog]:
[In Vitro]
SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively[1]. SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C24H24N2O7
[ Molecular Weight ]:
452.45700
[ Exact Mass ]:
452.15800
[ PSA ]:
105.09000
[ LogP ]:
2.81480
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport