7-(Dimethylamino)-4-methyl-2-benzopyrone

Names

[ CAS No. ]:
87-01-4

[ Name ]:
7-(Dimethylamino)-4-methyl-2-benzopyrone

[Synonym ]:
7-(Dimethylamino)-4-methyl-2-benzopyrone
7-(Dimethylamino)-4-methyl-2H-chromen-2-one
7-(Dimethylamino)-4-methyl-2H-1-benzopyran-2-one
T66 BOVJ E1 IN1&1
7-(Dimethylamino)-4-methylcoumarin
2H-1-Benzopyran-2-one, 7-(dimethylamino)-4-methyl-
EINECS 201-717-3
7-(Dimethylamino)-4-methylchromen-2-one
Coumarin, 7-(dimethylamino)-4-methyl-
MFCD00006862

Biological Activity

[Description]:

7-(Dimethylamino)-4-methylcoumarin is a coumarin. 7-(Dimethylamino)-4-methylcoumarin can be used in study coumarin fluorescent brightener solution[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Arient, Josef, et al. Liquid (dimethylamino)coumarin-based fluorescent whitener compositions. Czechoslovakia, CS189881. 1979-05-31

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
368.9±37.0 °C at 760 mmHg

[ Melting Point ]:
144-146°C

[ Molecular Formula ]:
C₁₂H₁₃NO₂

[ Molecular Weight ]:
203.237

[ Flash Point ]:
153.2±17.4 °C

[ Exact Mass ]:
203.094635

[ PSA ]:
33.45000

[ LogP ]:
3.09

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.595

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN6650000

CHEMICAL NAME :: Coumarin, 7-dimethylamino-4-methyl-

CAS REGISTRY NUMBER :: 87-01-4

BEILSTEIN REFERENCE NO. :: 0169992

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H13-N-O2

MOLECULAR WEIGHT :: 203.26

WISWESSER LINE NOTATION :: T66 BOVJ E1 IN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 26,619,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3890 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (104),45,1986

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .

[ Safety Phrases ]:
S22-S36/37/39

[ RTECS ]:
GN6650000

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%