Choline hydrogen tartrate

Names

[ CAS No. ]:
87-67-2

[ Name ]:
Choline hydrogen tartrate

[Synonym ]:
EINECS 201-763-4
MFCD00036332
2-Hydroxy-N,N,N-trimethylethanaminium 3-carboxy-2,3-dihydroxypropanoate
Choline hydrogen tartrate
Choline bitartrate

Biological Activity

[Description]:

Choline (bitartrate) is an essential nutrient, often associated with the B vitamins but not yet officially defined as a B vitamin[1]. Choline (bitartrate) plays an important role in synthesis of the neurotransmitter acetylcholine[2].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR

Signaling Pathways >> GPCR/G Protein >> mAChR

Research Areas >> Neurological Disease

[References]

[1]. Hollenbeck CB, et al. An introduction to the nutrition and metabolism of choline. Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):100-13.

[2]. Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159-65.

Chemical & Physical Properties

[ Density]:
1.47 g/cm3

[ Boiling Point ]:
399.3ºC at 760 mmHg

[ Melting Point ]:
151-153°C

[ Molecular Formula ]:
C₉H₁₉NO₇

[ Molecular Weight ]:
253.250

[ Flash Point ]:
209.4ºC

[ Exact Mass ]:
253.116150

[ PSA ]:
138.12000

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2923100000

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

A Phospholipid-Protein Complex from Krill with Antioxidative and Immunomodulating Properties Reduced Plasma Triacylglycerol and Hepatic Lipogenesis in Rats.

Mar. Drugs 13 , 4375-97, (2015)

Dietary intake of marine omega-3 polyunsaturated fatty acids (n-3 PUFAs) can change the plasma profile from atherogenic to cardioprotective. In addition, there is growing evidence that proteins of mar...

Accumulation of lipid in rat liver was induced by vitamin B₆ deficiency and was ameliorated by supplemental phosphatidylcholine in the diet.

Biosci. Biotechnol. Biochem. 79 , 1320-6, (2015)

We investigated the efficacy of supplementing the diet with pteroylmonoglutamic acid (PGA), choline, or phosphatidylcholine (PC) in ameliorating the lipid accumulation in rat liver that is induced by ...

Wheat Type (Class) Influences Development and Regression of Colon Cancer Risk Markers in Rats.

Nutr. Cancer 67 , 1283-92, (2015)

We previously found red wheat more effective than white wheat in reducing colon cancer risk in rats when fed during initiation and postinitiation stages. Here we examine the effect of wheat on colon c...