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Bis-5,5-nortrachelogenin

Names

[ CAS No. ]:
870480-56-1

[ Name ]:
Bis-5,5-nortrachelogenin

[Synonym ]:
2(3H)-Furanone, 4,4'-[(6,6'-dihydroxy-5,5'-dimethoxy[1,1'-biphenyl]-3,3'-diyl)bis(methylene)]bis[dihydro-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3S,4S,3'S,4'S)-
(3S,4S,3'S,4'S)-4,4'-[(6,6'-Dihydroxy-5,5'-dimethoxy-3,3'-biphenyldiyl)bis(methylene)]bis[3-hydroxy-3-(4-hydroxy-3-methoxybenzyl)dihydro-2(3H)-furanone]

Biological Activity

[Description]:

Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Wang LY, et al. Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities. Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
930.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C40H42O14

[ Molecular Weight ]:
746.75

[ Flash Point ]:
285.1±26.4 °C

[ Exact Mass ]:
746.257446

[ PSA ]:
210.90000

[ LogP ]:
0.48

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.659

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds