m-PEG5-NHS ester

Names

[ CAS No. ]:
874208-94-3

[ Name ]:
m-PEG5-NHS ester

[Synonym ]:
m-peg5-nhs ester

Biological Activity

[Description]:

m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₇NO₉

[ Molecular Weight ]:
377.38700

[ Exact Mass ]:
377.16900

[ PSA ]:
109.83000

m-PEG5-NHS ester

Names

Biological Activity

Chemical & Physical Properties

Related Compounds