6-((7-NITROBENZO[C][1,2,5]OXADIAZOL-4-YL)AMINO)HEXANOIC ACID

Names

[ Name ]:
6-((7-NITROBENZO[C][1,2,5]OXADIAZOL-4-YL)AMINO)HEXANOIC ACID

[Synonym ]:
7-Nitrobenzoxadiazole-6-aminohexanoic acid
N-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-6-aminohexanoic acid
6-(7-Nitrobenzofurazan-4-ylamino)hexanoic acid
N-(4-nitrobenz-2-oxa-1,3-diazol-7-yl)aminocaproic acid
Nbd-amha
6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanoic acid
NBD-X
NBD Hexanoic Acid
6-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoic acid
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylamino)hexanoic acid
N-(7-nitrobenz-2-oxa-1,3-diazole-4-yl)aminocaproic acid
6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid

Biological Activity

[Description]:

NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. McIntyre JC, et al. Synthesis and characterization of fluorescent neutral lipid analogs containing N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-aminohexanoic acid. Chem Phys Lipids. 1993 Dec;66(3):171-80.

Chemical & Physical Properties

[ Density]:
1.462

[ Boiling Point ]:
559.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₄N₄O₅

[ Molecular Weight ]:
294.26300

[ Exact Mass ]:
294.09600

[ PSA ]:
134.07000

[ LogP ]:
2.78410

[ Index of Refraction ]:
1.65

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331-H315-H319-H335

[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
22-26-36-45

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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