N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

Names

[ Name ]:
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

[Synonym ]:
9,12,15-Octadecatrienamide, N-[(3-methoxyphenyl)methyl]-, (9E,12E,15E)-
(9E,12E,15E)-N-(3-Methoxybenzyl)-9,12,15-octadecatrienamide

Biological Activity

[Description]:

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide is a macamide isolated from Maca (Lepidium meyenii Walp.) N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide induces mesenchymal stem cells osteogenic differentiation and consequent bone formation through activating the canonical Wnt/β‐catenin signaling pathway. N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide can be used for the research of osteoporosis[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> Wnt

Research Areas >> Metabolic Disease

[References]

[1]. Ting Wang, et al. N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide promotes bone formation via the canonical Wnt/β-catenin signaling . pathwayPhytother Res. 2019 Apr;33(4):1074-1083.

Chemical & Physical Properties

[ Density]:
0.961±0.06 g/cm3

[ Boiling Point ]:
562.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₃₉NO₂

[ Molecular Weight ]:
397.593

[ Flash Point ]:
293.8±30.1 °C

[ Exact Mass ]:
397.298065

[ LogP ]:
7.44

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.516

[ Storage condition ]:
-20°C

[ Water Solubility ]:
Insuluble (6.8E-4 g/L) (25 ºC)