Murraxocin

Names

[ Name ]:
Murraxocin

[Synonym ]:
8-(1-Ethoxy-2-hydroxy-3-methyl-3-butenyl)-7-methoxy-2H-chromen-2-one
8-(1-Ethoxy-2-hydroxy-3-methyl-3-buten-1-yl)-7-methoxy-2H-chromen-2-one
2H-1-Benzopyran-2-one, 8-(1-ethoxy-2-hydroxy-3-methyl-3-buten-1-yl)-7-methoxy-
Murraxocin

Biological Activity

[Description]:

Murpanicin (murraxocin) 是一种香豆素，是一种热敏瞬时受体电位香草酸 2 (TRPV2) 通道抑制剂。Murpanicin具有明显的抗炎、杀虫作用。

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Inflammation/Immunology

[References]

[1]. Shuo Yuan, et al. Rapid screening and identification of metabolites of murpanicin in rats by UHPLC/Q-TOF-MS/MS combined with diagnostic fragment ions (DFIs) and multiple mass defect filter. J Pharm Biomed Anal. 2022 May 10:213:114679.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
473.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₀O₅

[ Molecular Weight ]:
304.338

[ Flash Point ]:
171.0±22.2 °C

[ Exact Mass ]:
304.131073

[ PSA ]:
68.90000

[ LogP ]:
2.81

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.552

Safety Information

[ Hazard Codes ]:
Xi