L-Leucyl-2-naphthylaMide hydrochloride

Names

[ CAS No. ]:
893-36-7

[ Name ]:
L-Leucyl-2-naphthylaMide hydrochloride

[Synonym ]:
EINECS 212-970-4
L-Leucine |A-naphthylamide hydrochloride
EINECS 211-990-0
MFCD00034972
(S)-2-Amino-4-methyl-N-2-naphthylvaleramide monohydrochloride
Leucine-2-naphthylamide hydrochloride
L-Leucyl-2-naphthylaMide hydrochloride

Biological Activity

[Description]:

L-Leucine β-naphthylamide (hydrochloride) is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Boiling Point ]:
467ºC at 760 mmHg

[ Melting Point ]:
255-260 °C (dec.)

[ Molecular Formula ]:
C₁₆H₂₁ClN₂O

[ Molecular Weight ]:
292.80400

[ Flash Point ]:
236.2ºC

[ Exact Mass ]:
292.13400

[ PSA ]:
55.12000

[ LogP ]:
4.72700

[ Index of Refraction ]:
90 ° (C=1, H2O)

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: soluble

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Purification and properties of aminopeptidase and arylamidase from human liver.

J. Biochem. Tokyo 87 , 195, (1980)

Aminopeptidase and arylamidase from human liver were purified 1,580- and 1,130-fold, respectively, by ammonium sulfate fractionation, TEAE-cellulose and hydroxylapatite column chromatographies, and Se...