Fibrin

Names

[ Name ]:
Fibrin

[Synonym ]:
2-[(2-Aminoacetyl)amino]-N-methylacetamide
FIBRIN,TECH
2-amino-N-[(methylcarbamoyl)methyl]acetamide
MFCD00131058
EINECS 232-597-0
FIBRIN

Biological Activity

[Description]:

Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Paulson CN, et al. The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA bindingprotein Mcm10. Open Biol. 2019 Aug 30;9(8):190117.

Chemical & Physical Properties

[ Density]:
1.146g/cm3

[ Boiling Point ]:
471.7ºC at 760mmHg

[ Molecular Formula ]:
C₅H₁₁N₃O₂

[ Molecular Weight ]:
145.16000

[ Flash Point ]:
239.1ºC

[ Exact Mass ]:
145.08500

[ PSA ]:
91.20000

[ LogP ]:
0.18820

[ Index of Refraction ]:
1.48

[ Storage condition ]:
2-8°C

Safety Information

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Thrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in mice.

J. Pharmacol. Exp. Ther. 351(2) , 288-97, (2014)

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of obesity and metabolic syndrome. Robust coagulation cascade activation is common in obese patients with NAFLD. We identified a c...

Novel thrombolytic protease from edible and medicinal plant Aster yomena (Kitam.) Honda with anticoagulant activity: purification and partial characterization.

J. Biosci. Bioeng. 118(4) , 372-7, (2014)

A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase showed a molecular weight of 50 kDa by SDS-P...

The effect of etanercept on lung leukocyte margination and fibrin deposition after cardiac surgery.

Am. J. Respir. Crit. Care Med. 188(6) , 751-4, (2013)