β-D-Mannopyranuronic acid

[Description]:

Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties[1][2][3].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor

Research Areas >> Endocrinology

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[In Vitro]

Alginic acid (AA) is a kind of polysaccharide extracted from brown seaweeds and has been widely used in food industry[2].

[References]

[1]. Guo X, et al. Structures, properties and application of alginic acid: A review. Int J Biol Macromol. 2020;162:618-628.

[2]. Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099.

[3]. Jeong HJ, et al. Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation. Clin Exp Allergy. 2006;36(6):785-794.

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
495.2±45.0 °C at 760 mmHg

[ Melting Point ]:
300 °C

[ Molecular Formula ]:
C₁₈H₂₆O₁₉

[ Molecular Weight ]:
194.139

[ Flash Point ]:
211.1±22.2 °C

[ Exact Mass ]:
194.042648

[ PSA ]:
127.45000

[ LogP ]:
-2.88

[ Appearance of Characters ]:
Powder | White to pale yellow to beige

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.685

[ Water Solubility ]:
H2O: insoluble, but swells | Insoluble in water.

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
24/25-36-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
AZ5775000

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