UBP 310

Names

[ CAS No. ]:
902464-46-4

[ Name ]:
UBP 310

Biological Activity

[Description]:

UBP310 is a selective GluR5 antagonist, with a Kd of 130 nM[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[Target]

GluR5[1]

[In Vitro]

UBP310 binds to GluR5 S1S2 with an affinity of 130 nM and shows 12,700-fold selectivity for GluR5 versus GluR6 and 830-fold selectivity for GluR5 versus GluR2[1].

[References]

[1]. Mark L Mayer, et al. Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J Neurosci. 2006 Mar 15;26(11):2852-61.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₅N₃O₆S

[ Molecular Weight ]:
353.35000

[ Exact Mass ]:
353.06800

[ PSA ]:
172.86000

[ LogP ]:
0.23860

UBP 310

Names

Biological Activity

Chemical & Physical Properties

Related Compounds