Aspergillus acid protease

Names

[ Name ]:
Aspergillus acid protease

[Synonym ]:
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-
1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic Acid
T66 BV EN GNJ CVQ E2 H1
Acide 1-etil-7-metil-1,8-naftiridin-4-one-3-carbossilico
NegGram
WIN-18320
WINTOMYLON
Acide nalidixico
nalidixic acid
Aspergillus acid protease
EINECS 232-796-2

Biological Activity

[Description]:

Aspergillopepsin I (Aspergillus acid protease) is an aspartic endopeptidase that catalyses the hydrolysis of peptide bonds in proteins, with broad specificity[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
413.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₂N₂O₃

[ Molecular Weight ]:
232.235

[ Flash Point ]:
203.6±28.7 °C

[ Exact Mass ]:
232.084793

[ LogP ]:
1.19

[ Appearance of Characters ]:
white powder

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.605

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
5-20 mg/mL

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
37/38-41-42-36/37/38-42/43-20

[ Safety Phrases ]:
23-24-26-36/37/39-36/37-22-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UK9595000

Articles

[Modification of two tyrosine residues in aspergillopepsin A by p-nitrophenyldiazonium chloride].

Biokhimiia 46(2) , 369-75, (1981)

p-Nitrophenyldiazonium chloride was found to modify the Tyr-75 and Tyr-189 residues in aspergillopepsin A. Incubation of the protein with a 45-fold molar excess of the reagent at pH 5,2 results in the...

Sequences from the aspergillopepsin PEP gene of Aspergillus fumigatus: evidence on their use in selective PCR identification of Aspergillus species in infected clinical samples.

FEMS Immunol. Med. Microbiol. 25(3) , 255-64, (1999)

In immunodeficient patients, Aspergillus species emerge as circumstantial pathogens. Aspergillus fumigatus is a distant first among the pathogenic aspergilli, which cause deep-seated mycoses. Sequence...

The site of diazoacetyl inhibitor attachment to acid proteinase of Aspergillus awamori--an analog of penicillopepsin and pepsin.

Biochem. Biophys. Res. Commun. 49(4) , 1075-81, (1972)