Bifemelane

Names

[ Name ]:
Bifemelane

[Synonym ]:
1-Butanamine, N-methyl-4-[2-(phenylmethyl)phenoxy]-
Bifemelanum [Latin]
2-Benzyl-1-[4-(methylamino)butoxy]benzene
4-(2-Benzylphenoxy)-N-methylbutan-1-amine
2-(4-N-methylaminobutoxy)diphenylmethane
2-(4-methylaminobutoxy)diphenylmethane
4-(o-benzylphenoxy)-n-methylbutylamine
Bifemelane
4-(2-Benzylphenoxy)-N-methyl-1-butanamine
N-Methyl 4-[2-(phenylmethyl)phenoxy]-1-butanamine
Bifemelano [Spanish]
Bifemelane [INN]

Biological Activity

[Description]:

Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca2+ stores and the second by capacitive entry through store–operated Ca2+ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Neurological Disease

[References]

[1]. YoshitokuYoshida, et al. A Novel Effect of Bifemelane, a Nootropic Drug, on Intracellular Ca2+ Levels in Rat Cerebral Astrocytes.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
395.4±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₃NO

[ Molecular Weight ]:
269.38

[ Flash Point ]:
169.2±14.0 °C

[ Exact Mass ]:
269.177979

[ PSA ]:
21.26000

[ LogP ]:
4.19

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.543

[ Storage condition ]:
Desiccate at RT

Safety Information

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%