Neochamaejasmin A

Names

[ Name ]:
Neochamaejasmin A

[Synonym ]:
Neochamaejasmin A

Biological Activity

[Description]:

Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and Apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Liu WK, et al. Involvement of p21 and FasL in induction of cell cycle arrest and apoptosis by neochamaejasmin A in human prostate LNCaP cancer cells. J Nat Prod. 2008 May;71(5):842-6.

[2]. Ding Y, et al. Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. Oxid Med Cell Longev. 2020 Jan 20;2020:3237150.

Chemical & Physical Properties

[ Density]:
1.594±0.06 g/cm3

[ Molecular Formula ]:
C₃₀H₂₂O₁₀

[ Molecular Weight ]:
542.49000

[ Exact Mass ]:
542.12100

[ PSA ]:
173.98000

[ LogP ]:
4.48560

[ Water Solubility ]:
Insuluble (1.0E-4 g/L) (25 ºC)

Neochamaejasmin A

Names

Biological Activity

Chemical & Physical Properties

Related Compounds